SCHEMBL8777625

SCHEMBL8777625

CCOc1cc(N(CC)CC)ccc1C(OCc1ccc(Cl)cc1)c1ccc(N(C)C)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 3/20 0.38
POLB P06746 3/20 0.36
NPC1 O15118 1/20 0.36
TACR2 P21452 2/20 0.36
RXFP1 Q9HBX9 1/20 0.36
CYP19A1 P11511 1/20 0.35
CNR2 P34972 4/20 0.35
TDP1 Q9NUW8 2/20 0.34
KMT2A Q03164 4/20 0.34
MEN1 O00255 3/20 0.34
ATM Q13315 2/20 0.34
FFAR1 O14842 1/20 0.34
TP53 P04637 2/20 0.33
GAA P10253 1/20 0.33
MAPT P10636 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP2C9 P11712 2/20 0.33
CNR1 P21554 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777736 0.90 APP (0.41) POLBNPC1TDP1KMT2AMEN1
SCHEMBL8777700 0.90 MEN1 (0.35) POLBCNR2TDP1KMT2AMEN1
SCHEMBL8777724 0.89 CALM1 (0.34) TDP1KMT2AMEN1GAACYP3A4
SCHEMBL8777741 0.89 SLC2A1 (0.42) POLBTDP1KMT2AMEN1
SCHEMBL8777670 0.89 MAPK1 (0.38) POLBRXFP1CNR2TDP1KMT2A
SCHEMBL8777563 0.83 NOX1 (0.40) CNR2KMT2AMEN1MAPTCNR1
SCHEMBL8777653 0.82 RXRA (0.38) TDP1KMT2AMEN1GAAMAPT
SCHEMBL8777629 0.81 ALDH1A1 (0.37) TDP1KMT2AMEN1GAAMAPT
SCHEMBL8777642 0.81 TDP1 (0.41) POLBNPC1CNR2TDP1KMT2A
SCHEMBL8777842 0.81 ALDH1A1 (0.39) TDP1KMT2AMEN1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed