SCHEMBL8777736

SCHEMBL8777736

CCOc1ccc(COC(c2ccc(N(C)C)cc2)c2ccc(N(CC)CC)cc2OCC)cc1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
APP P05067 5/20 0.41
TDP1 Q9NUW8 2/20 0.37
ACACB O00763 1/20 0.35
SLC2A1 P11166 1/20 0.35
ALDH1A1 P00352 2/20 0.34
NPC1 O15118 1/20 0.34
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
MAOB P27338 1/20 0.34
MEN1 O00255 3/20 0.34
KMT2A Q03164 3/20 0.34
MAPK1 P28482 2/20 0.34
NOX1 Q9Y5S8 1/20 0.33
CALM1 P0DP23 2/20 0.33
POLB P06746 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8777741 0.95 SLC2A1 (0.42) APPTDP1SLC2A1ALDH1A1MEN1
SCHEMBL8777700 0.91 MEN1 (0.35) APPTDP1ALDH1A1MEN1KMT2A
SCHEMBL8777625 0.90 CCR5 (0.38) TDP1NPC1LMNAMAPTMEN1
SCHEMBL8777724 0.90 CALM1 (0.34) APPTDP1ALDH1A1MEN1KMT2A
SCHEMBL8777670 0.90 MAPK1 (0.38) TDP1ALDH1A1MAPTMEN1KMT2A
SCHEMBL8777563 0.84 NOX1 (0.40) LMNAMAPTRAB9AMEN1KMT2A
SCHEMBL8777653 0.83 RXRA (0.38) TDP1SLC2A1ALDH1A1MAPTMEN1
SCHEMBL8777629 0.82 ALDH1A1 (0.37) TDP1ACACBSLC2A1ALDH1A1LMNA
SCHEMBL8777642 0.81 TDP1 (0.41) TDP1SLC2A1ALDH1A1NPC1MAPT
SCHEMBL8777842 0.81 ALDH1A1 (0.39) TDP1SLC2A1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0587184-B1 Pressure sensitive recording materials NEW OJI PAPER CO LTD (JP) 1997-12-29 EP disclosed
US-5478793-A Basic dye-containing layer and color accetpor-containing layer formed on same or different surfaces; basic dye enclosed in synthetic polymer microcapsules, color acceptor is activated clay containing silica KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1995-12-26 US disclosed
EP-0587184-A2 Pressure sensitive recording materials NEW OJI PAPER CO., LTD. (JP) 1994-03-16 EP disclosed