Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778007 | 0.84 | LMNA (0.50) | LMNAALOX5EPHX2CYP3A4TDP1 | |
| SCHEMBL9088287 | 0.83 | PTGER4 (0.48) | MAPTLMNAPTGER4PTGER2KMT2A | |
| SCHEMBL4728356 | 0.82 | MAPT (0.51) | MAPTLMNAPTGER4PTGER2KMT2A | |
| SCHEMBL8778095 | 0.81 | FFAR1 (0.47) | MAPTLMNAALOX5EPHX2CHRM3 | |
| SCHEMBL6840223 | 0.80 | PTGER4 (0.64) | PTGER4PTGER2KMT2ATEAD1ALOX5 | |
| SCHEMBL31173731 | 0.80 | MLYCD (0.63) | LMNAKMT2ANPC1RAB9AMLYCD | |
| SCHEMBL1052230 | 0.80 | MLYCD (0.63) | LMNAKMT2ANPC1RAB9AMLYCD | |
| SCHEMBL9204775 | 0.77 | PTGER4 (0.45) | MAPTLMNAPTGER4PTGER2KMT2A | |
| SCHEMBL8777936 | 0.74 | TP53 (0.52) | MAPTLMNAKMT2AALOX5EPHX2 | |
| SCHEMBL18414328 | 0.74 | PPARG (0.53) | KMT2AMLYCDCHRM3MEN1PLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651743-B1 | INDOLINYL N-HYDROXYUREA AND N-HYDROXAMIC ACID DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER (US) | 1997-12-17 | — | — | EP | disclosed |