Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4728356 | 0.89 | MAPT (0.51) | LMNAMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL8778007 | 0.83 | LMNA (0.50) | LMNAALOX5EPHX2KDM4EALDH1A1 | |
| SCHEMBL9088999 | 0.83 | KDM4E (0.45) | LMNAALOX5CCR8FAAHKDM4E | |
| SCHEMBL8777898 | 0.81 | MAPT (0.51) | CHRM3LMNAALOX5EPHX2MAPT | |
| SCHEMBL8778025 | 0.79 | PTGER4 (0.52) | LMNAMAPTALDH1A1SMN1; SMN2TP53 | |
| Hydrochloric Acid SCHEMBL5709327 | 0.79 | FFAR1 (0.61) | FFAR1MAPK14KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8777936 | 0.78 | TP53 (0.52) | CHRM3LMNAALOX5EPHX2MAPT | |
| SCHEMBL8777937 | 0.77 | ALOX5 (0.55) | LMNAALOX5EPHX2MAPTALDH1A1 | |
| SCHEMBL16494249 | 0.74 | ACHE (0.55) | LMNAMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL8777957 | 0.74 | LMNA (0.48) | LMNAMAPTTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0651743-B1 | INDOLINYL N-HYDROXYUREA AND N-HYDROXAMIC ACID DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER (US) | 1997-12-17 | — | — | EP | disclosed |