Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 4/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778662 | 0.84 | MEN1 (0.37) | SCN9AKMT2AALDH1A1F10 | |
| SCHEMBL8068683 | 0.84 | SMN1; SMN2 (0.41) | HPGDSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8778653 | 0.83 | SLC9A1 (0.45) | — | |
| Hydrochloric Acid SCHEMBL8059609 | 0.83 | SMN1; SMN2 (0.40) | HPGDSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8743793 | 0.82 | MRGPRX1 (0.44) | HPGDSMN1; SMN2LMNAF10F2 | |
| SCHEMBL8446348 | 0.81 | CA2 (0.43) | KMT2AHTTKDM4EALDH1A1F10 | |
| Hydrochloric Acid SCHEMBL8743783 | 0.81 | MRGPRX1 (0.44) | HPGDSMN1; SMN2LMNAF10F2 | |
| SCHEMBL8379266 | 0.81 | HPGD (0.41) | HPGDKMT2ASMN1; SMN2LMNAHTT | |
| SCHEMBL8743801 | 0.81 | PARP10 (0.40) | HPGDSMN1; SMN2HTTF10 | |
| Hydrochloric Acid SCHEMBL8059467 | 0.80 | CA2 (0.42) | KMT2AHTTKDM4EALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640593-B1 | Substituted benzoylguanidines, process for their preparation, their use as medicine or in diagnostic and medicines containing them | HOECHST AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| EP-0640593-A1 | Substituted benzoylguanidines, process for their preparation, their use as medicine or in diagnostic and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-03-01 | — | — | EP | disclosed |