Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 12/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.39 |
| ▸ | CIT | O14578 | 4/20 | 0.36 |
| ▸ | REN | P00797 | 1/20 | 0.35 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779223 | 0.90 | AAK1 (0.39) | AAK1CITLARS1 | |
| SCHEMBL8779183 | 0.89 | REN (0.35) | LNPEPREN | |
| SCHEMBL8779140 | 0.89 | REN (0.35) | LNPEPREN | |
| SCHEMBL8779334 | 0.86 | LNPEP (0.42) | AAK1LNPEPCITLARS1 | |
| SCHEMBL8880821 | 0.84 | AAK1 (0.40) | AAK1LNPEPCITRENLARS1 | |
| SCHEMBL8779387 | 0.84 | AAK1 (0.38) | AAK1CITLARS1 | |
| SCHEMBL8779239 | 0.83 | LNPEP (0.40) | AAK1LNPEP | |
| SCHEMBL8779087 | 0.81 | IKBKB (0.34) | LNPEP | |
| SCHEMBL8779229 | 0.81 | IRAK4 (0.40) | AAK1LNPEP | |
| SCHEMBL8779157 | 0.80 | XIAP (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0661269-B1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AG (DE) | 1997-03-26 | — | — | EP | disclosed |
| EP-0661269-A1 | Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-07-05 | — | — | EP | disclosed |