Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CUL4A | Q13619 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779305 | 0.84 | LMNA (0.61) | LMNAALDH1A1SMN1; SMN2POLBMAPT | |
| P-Xylene SCHEMBL8779430 | 0.81 | SMN1; SMN2 (0.57) | LMNAALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL8779375 | 0.78 | TOP1 (0.37) | LMNAALDH1A1SMN1; SMN2POLBMAPT | |
| P-Cresol SCHEMBL8779429 | 0.77 | SMN1; SMN2 (0.49) | LMNAALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL280615 | 0.76 | LMNA (1.00) | LMNAALDH1A1SMN1; SMN2POLBMAPT | |
| Acetic Acid Phenyl Ester SCHEMBL8045094 | 0.75 | ELANE (0.51) | LMNAALDH1A1POLBMAPTPKM | |
| Ammonia Solution, Strong SCHEMBL27903026 | 0.74 | LMNA (0.95) | LMNAALDH1A1SMN1; SMN2POLBMAPT | |
| SCHEMBL7798435 | 0.74 | LMNA (0.95) | LMNAALDH1A1SMN1; SMN2POLBMAPT | |
| Hydrogen Sulfide SCHEMBL27637439 | 0.74 | LMNA (0.95) | LMNAALDH1A1SMN1; SMN2POLBMAPT | |
| Phosphine SCHEMBL27576228 | 0.74 | LMNA (0.95) | LMNAALDH1A1SMN1; SMN2POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | claimed |