Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RECQL | P46063 | 3/20 | 0.32 |
| ▸ | BLM | P54132 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | APEX1 | P27695 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779376 | 0.85 | ALDH1A1 (0.41) | TOP1GAARAB9AALDH1A1HPGD | |
| SCHEMBL8779352 | 0.82 | NR3C1 (0.44) | GAARAB9AALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL8779346 | 0.78 | LMNA (0.57) | POLBRAB9AELANEALDH1A1KMT2A | |
| SCHEMBL10053943 | 0.77 | TOP1 (0.53) | TOP1POLBGAARAB9AHTT | |
| SCHEMBL8779305 | 0.76 | LMNA (0.61) | POLBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL10053942 | 0.71 | ACHE (0.54) | TOP1POLBGAAHTTELANE | |
| SCHEMBL8779330 | 0.70 | RAB9A (0.53) | POLBGAARAB9AHTTALDH1A1 | |
| SCHEMBL13775501 | 0.67 | ACHE (0.58) | POLBGAAHTTALDH1A1KMT2A | |
| SCHEMBL94066 | 0.66 | — | — | |
| SCHEMBL21579506 | 0.65 | MAPK1 (0.57) | TOP1POLBGAARAB9AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | claimed |