Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779346 | 0.84 | LMNA (0.57) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL8779376 | 0.81 | ALDH1A1 (0.41) | LMNAKMT2AMEN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL280618 | 0.78 | LMNA (1.00) | LMNAMAPTPOLBKMT2ACYP3A4 | |
| SCHEMBL30638434 | 0.78 | LMNA (1.00) | LMNAMAPTPOLBKMT2ACYP3A4 | |
| SCHEMBL8779352 | 0.78 | NR3C1 (0.44) | CYP3A4ALDH1A1ACHESMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27920738 | 0.77 | LMNA (0.96) | LMNAMAPTPOLBKMT2ACYP3A4 | |
| SCHEMBL27808382 | 0.77 | LMNA (0.96) | LMNAMAPTPOLBKMT2ACYP3A4 | |
| SCHEMBL27808339 | 0.77 | LMNA (0.96) | LMNAMAPTPOLBKMT2ACYP3A4 | |
| Metacresol SCHEMBL8779348 | 0.76 | ACHE (0.53) | LMNAMAPTPOLBKMT2AMEN1 | |
| SCHEMBL8779375 | 0.76 | TOP1 (0.37) | LMNAMAPTPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0579129-B1 | Thiadiazole derivatives for the treatment of depressive states | CT LAB FARM SRL (IT) | 1997-03-05 | — | — | EP | claimed |