SCHEMBL8779509

SCHEMBL8779509

C1=CC([Hf]C2C=Cc3ccccc32)c2ccccc21.Cl[Si](Cl)(c1ccccc1)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8779649 0.84 HTR2A (0.33) HTR6HTR2A
SCHEMBL4918618 0.84 HTR2A (0.40) HTR6HTR2A
SCHEMBL6324320 0.84 HTR2A (0.40) HTR6HTR2A
Biphenyl SCHEMBL9278337 0.80 ALDH1A1 (0.36) HTR6HTR2A
Ethylene SCHEMBL6917299 0.80 HTR2A (0.38) HTR6HTR2A
SCHEMBL8779540 0.79 HTR2A (0.33) HTR6HTR2A
SCHEMBL15189741 0.77 HTR2A (0.35) HTR6HTR2A
SCHEMBL8779476 0.77 HTR6 (0.31) HTR6HTR2A
SCHEMBL8779526 0.77 HTR6 (0.31) HTR6HTR2A
SCHEMBL6917288 0.70 HTR2A (0.33) HTR6HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0730003-B1 Polypropylene resin composition and molded product TOSOH CORP (JP) 1997-12-29 EP disclosed
US-5608008-A ETHYLENE-A-OLEFIN COPOLYMER ELASTOMER TOSOH CORPORATION (JP) 1997-03-04 US disclosed
EP-0730003-A1 Polypropylene resin composition and molded product Tosoh Corporation (JP) 1996-09-04 EP disclosed