Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14879020 | 0.85 | LMNA (0.47) | TRPM8KMT2AMEN1TP53LMNA | |
| SCHEMBL8178829 | 0.83 | KMT2A (0.42) | TRPM8KMT2AMEN1TP53LMNA | |
| SCHEMBL8177891 | 0.81 | ATM (0.46) | TRPM8KMT2AMEN1TP53LMNA | |
| SCHEMBL7601412 | 0.80 | ALDH1A1 (0.44) | TRPM8KMT2AMEN1TP53LMNA | |
| SCHEMBL8779792 | 0.80 | TRPM8 (0.50) | TRPM8KMT2AMEN1TP53LMNA | |
| SCHEMBL8779768 | 0.80 | TRPM8 (0.43) | TRPM8KMT2AMEN1TP53LMNA | |
| SCHEMBL8166612 | 0.80 | KMT2A (0.43) | TRPM8KMT2AMEN1TP53LMNA | |
| SCHEMBL19207734 | 0.78 | LMNA (0.45) | TRPM8KMT2AMEN1TP53LMNA | |
| SCHEMBL8779621 | 0.78 | TRPM8 (0.51) | TRPM8KMT2AMEN1TP53LMNA | |
| SCHEMBL2325685 | 0.75 | NPSR1 (0.44) | KMT2AMEN1CYP3A4ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105906532-A | Synthetic method of N-methoxy-N-2-methylphenylcarbamate | 安徽广信农化股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| CN-105906532-A | Synthetic method of N-methoxy-N-2-methylphenylcarbamate | 安徽广信农化股份有限公司 | 2016-08-31 | — | — | CN | disclosed |
| EP-0525197-B1 | 3-BENZYLIDENE-1-CARBAMOYL-2-PYRROLIDONE ANALOGS | SHIONOGI & CO (JP) | 1997-08-27 | — | — | EP | disclosed |
| US-5319100-A | Antiinflammatory agent which does not cause stomach diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| US-5319099-A | Antiinflammatory agent which does not cause stomach diseases | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1994-06-07 | — | — | US | disclosed |
| EP-0525197-A1 | 3-BENZYLIDENE-1-CARBAMOYL-2-PYRROLIDONE ANALOG | SHIONOGI SEIYAKU KABUSHIKI KAISHA (JP) | 1993-02-03 | — | — | EP | disclosed |