SCHEMBL3399259

SCHEMBL3399259

Cc1ccc(C(=O)O)cc1N=C=S

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
LMNA P02545 2/20 0.46
MAPT P10636 2/20 0.45
KDM4E B2RXH2 2/20 0.44
PLA2G1B P04054 1/20 0.44
HPGD P15428 1/20 0.44
ATG4B Q9Y4P1 1/20 0.44
TSHR P16473 2/20 0.44
NEU3 Q9UQ49 4/20 0.41
MYC P01106 1/20 0.40
ESR1 P03372 1/20 0.40
ALOX15 P16050 1/20 0.40
PTPN7 P35236 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TRPA1 O75762 1/20 0.40
CYP3A4 P08684 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
GRM1 Q13255 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2344531 0.86 ALDH1A1 (0.46) ALDH1A1LMNAMAPTHPGDTRPA1
SCHEMBL3398382 0.86 TSHR (0.44) ALDH1A1MAPTKDM4ETSHRNEU3
SCHEMBL6114050 0.85 ALDH1A1 (0.44) ALDH1A1LMNAMAPTKDM4ENEU3
SCHEMBL8779816 0.84 NEU3 (0.42) ALDH1A1MAPTKDM4ETSHRNEU3
SCHEMBL3320428 0.82 CA1 (0.45) ALDH1A1LMNAMAPTKDM4EHPGD
SCHEMBL2899363 0.81 NEU3 (0.45) MAPTKDM4ETSHRNEU3MYC
SCHEMBL2923061 0.79 MAPK14 (0.50) HPGDSMN1; SMN2CYP1A2
SCHEMBL2919702 0.79 CA1 (0.57) ALDH1A1LMNAMAPTKDM4ETSHR
SCHEMBL10079468 0.78 MAPT (0.51) ALDH1A1LMNAMAPTKDM4EPLA2G1B
SCHEMBL3003942 0.78 TPMT (0.38) ALDH1A1LMNAMAPTTSHRNEU3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8367857-B2 Method for producing isothiocyanate compound having carboxyl group NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2013-02-05 US disclosed
US-20100312000-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2010-12-09 US disclosed
EP-2248800-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP Nissan Chemical Industries, Ltd. (JP) 2010-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100312000-A1 METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP CBS, CTH, TST ALDH1A1 820/4885LMNA 4848/4885MAPT 4257/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.