Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.57 |
| ▸ | CA2 | P00918 | 3/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.57 |
| ▸ | CA4 | P22748 | 2/20 | 0.57 |
| ▸ | CA6 | P23280 | 2/20 | 0.57 |
| ▸ | CA7 | P43166 | 2/20 | 0.57 |
| ▸ | CA9 | Q16790 | 2/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.57 |
| ▸ | TPMT | P51580 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | TTR | P02766 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6118124 | 0.86 | MAPK1 (0.50) | CA1CA2CA12CA4CA6 | |
| SCHEMBL6118516 | 0.86 | MAPT (0.53) | CA1CA2CA12CA4CA6 | |
| SCHEMBL13219859 | 0.80 | CA12 (0.65) | CA1CA2CA12CA4CA6 | |
| SCHEMBL3007486 | 0.80 | CA1 (0.49) | CA1CA2CA12CA4CA6 | |
| SCHEMBL8779816 | 0.80 | NEU3 (0.42) | CA1CA2CA12CA4CA6 | |
| SCHEMBL3399259 | 0.79 | ALDH1A1 (0.46) | LMNATSHRALDH1A1KDM4EMAPT | |
| SCHEMBL2899363 | 0.77 | NEU3 (0.45) | CA1CA2CA12CA4CA6 | |
| SCHEMBL1457686 | 0.76 | CA12 (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL30940602 | 0.76 | CA12 (0.52) | CA1CA2CA12CA7CA9 | |
| SCHEMBL3398382 | 0.76 | TSHR (0.44) | CA1CA2CA12CA4CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117342991-A | Sustained-release high-alkaline cement reinforcing agent and preparation method and application thereof | 华新水泥股份有限公司 | 2024-01-05 | — | — | CN | claimed |
| CN-117342991-A | Sustained-release high-alkaline cement reinforcing agent and preparation method and application thereof | 华新水泥股份有限公司 | 2024-01-05 | — | — | CN | disclosed |
| CN-101965331-B | Method for producing isothiocyanate compound having carboxyl group | NISSAN CHEMICAL IND LTD | 2014-04-16 | — | — | CN | disclosed |
| US-8367857-B2 | Method for producing isothiocyanate compound having carboxyl group | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2013-02-05 | — | — | US | disclosed |
| CN-101965331-A | Method for producing isothiocyanate compound having carboxyl group | NISSAN CHEMICAL IND LTD | 2011-02-02 | — | — | CN | disclosed |
| US-7855288-B2 | Pyrrolo [1,2-d] [1,2-4] triazine as inhibitors of c-Jun N terminal kinases (JNK) and p-38 kinases | NOVARTIS AG (CH) | 2010-12-21 | — | — | US | disclosed |
| US-20100312000-A1 | METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP | NISSAN CHEMICAL INDUSTRIES LIMITED (JP) | 2010-12-09 | — | — | US | disclosed |
| EP-2248800-A1 | METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP | Nissan Chemical Industries, Ltd. (JP) | 2010-11-10 | — | — | EP | disclosed |
| EP-1807431-B1 | PYRROLO[1,2-D][1,2-4]TRIAZINE AS INHIBITORS OF C-JUN N-TERMINAL KINASES (JNK) AND P-38 KINASES | NOVARTIS AG (CH) | 2010-09-08 | — | — | EP | disclosed |
| US-20080253988-A1 | Pyrrolo [1,2-D] [1,2-4] Triazine as Inhibitors of C-Jun N Terminal Kinases (Jnk) and P-38 Kinases | NOVARTIS AG (CH) | 2008-10-16 | — | — | US | disclosed |
| EP-1807431-A1 | PYRROLO[1,2-D][1,2-4]TRIAZINE AS INHIBITORS OF C-JUN N-TERMINAL KINASES (JNK) AND P-38 KINASES | Novartis AG (CH) | 2007-07-18 | — | — | EP | disclosed |
| WO-2006047354-A1 | PYRROLO [1,2-D][1,2-4]TRIAZINE AS INHIBITORS OF C-JUN N TERMINAL KINASES (JNK) AND P-38 KINASES | NOVARTIS AG (CH) | 2006-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080253988-A1 | Pyrrolo [1,2-D] [1,2-4] Triazine as Inhibitors of C-Jun N Terminal Kinases (Jnk) and P-38 Kinases | MAPK8, MAP3K8, STK38 | CA1 4100/4885CA2 4556/4885CA12 4746/4885 |
| US-20100312000-A1 | METHOD FOR PRODUCING ISOTHIOCYANATE COMPOUND HAVING CARBOXYL GROUP | CBS, CTH, TST | CA1 1100/4885CA2 501/4885CA12 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.