Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 10/20 | 0.47 |
| ▸ | ITGAV | P06756 | 10/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.45 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | NOS1 | P29475 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779881 | 1.00 | HDAC3 (0.48) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL9687293 | 0.87 | EGLN1 (0.43) | IDO1NOS1AAK1CASP1 | |
| SCHEMBL8779934 | 0.87 | AAK1 (0.45) | ITGB3ITGAVIDO1NOS1AAK1 | |
| SCHEMBL6528186 | 0.76 | PIN1 (0.59) | ITGB3ITGAVITGA2B | |
| SCHEMBL21240753 | 0.76 | DAGLA (0.54) | DAGLAFAAH | |
| SCHEMBL7419324 | 0.76 | CASP1 (0.54) | IDO1CASP1 | |
| SCHEMBL7419321 | 0.76 | CASP1 (0.54) | IDO1CASP1 | |
| SCHEMBL9516878 | 0.76 | PADI4 (0.51) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL4280674 | 0.76 | CASP1 (0.67) | CASP1 | |
| SCHEMBL4280669 | 0.76 | CASP1 (0.67) | CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0539057-B1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PROD (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0539057-A1 | Benzimidazole phosphono-amino acids | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-04-28 | — | — | EP | disclosed |
| US-5124319-A | Administering for treatment of neuropathological disorders induced by overstimulation of excitatory amino acid receptors | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |