Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TPH1 | P17752 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7338043 | 0.84 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2HPGDGLANPSR1 | |
| SCHEMBL1768600 | 0.70 | SLC7A5 (0.68) | LNPEPSLC7A5TPH1MAPTKDM4E | |
| SCHEMBL6776885 | 0.70 | SLC7A5 (0.68) | LNPEPSLC7A5TPH1MAPTKDM4E | |
| SCHEMBL1768596 | 0.70 | SLC7A5 (0.68) | LNPEPSLC7A5TPH1MAPTKDM4E | |
| SCHEMBL7223676 | 0.70 | TP53 (0.56) | ALDH1A1LMNAMAPTRAB9AKDM4E | |
| SCHEMBL14987948 | 0.69 | MAPK1 (0.67) | ALDH1A1SMN1; SMN2HPGDGLANPSR1 | |
| SCHEMBL6478714 | 0.68 | LMNA (0.52) | SMN1; SMN2MEN1KMT2AACACBLMNA | |
| SCHEMBL26606524 | 0.68 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2HPGDNPSR1MEN1 | |
| SCHEMBL15019652 | 0.67 | LOXL2 (0.59) | ALDH1A1SMN1; SMN2HPGDLNPEPGAA | |
| SCHEMBL15019650 | 0.67 | LOXL2 (0.59) | ALDH1A1SMN1; SMN2HPGDLNPEPGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788511-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |