Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780699 | 0.95 | ALDH1A1 (0.46) | ALDH1A1HSD17B10CYP1B1HIF1AHPGD | |
| SCHEMBL13249124 | 0.91 | ALDH1A1 (0.41) | ALDH1A1HSD17B10CYP1B1HIF1AHPGD | |
| SCHEMBL31442400 | 0.89 | MCL1 (0.47) | ALDH1A1CYP1B1HPGDMCL1ACMSD | |
| SCHEMBL18820531 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HSD17B10CYP1B1HIF1AHPGD | |
| SCHEMBL8780627 | 0.83 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP1B1HIF1AHPGD | |
| SCHEMBL14101579 | 0.82 | MCL1 (0.40) | ALDH1A1HSD17B10CYP1B1HPGDCYP1A2 | |
| SCHEMBL14101636 | 0.82 | CYP1A2 (0.44) | ALDH1A1HSD17B10CYP1B1HPGDCYP1A2 | |
| SCHEMBL1527420 | 0.82 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP1B1HIF1AHPGD | |
| SCHEMBL17945491 | 0.81 | ALOX5 (0.39) | ALDH1A1HPGDMCL1ACMSDALOX5 | |
| SCHEMBL14101578 | 0.81 | CYP1A2 (0.42) | ALDH1A1HSD17B10CYP1B1HPGDCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-9499459-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2016-11-22 | — | — | US | disclosed |
| US-8986852-B2 | Benzanthracene derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| US-8986852-B2 | Benzanthracene derivatives for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-03-24 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2012-05-24 | — | — | US | disclosed |
| US-20100187505-A1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
| US-20100187505-A1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | IDEMITSU KOSAN CO., LTD. (JP) | 2010-07-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100187505-A1 | BENZANTHRACENE DERIVATIVES FOR ORGANIC ELECTROLUMINESCENT DEVICES | KCNT1, KCNC1, TMEM109 | ALDH1A1 26/4885HSD17B10 936/4885CYP1B1 36/4885 |
| US-20120126180-A1 | NOVEL MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MYB, L1CAM, SLC25A21 | ALDH1A1 507/4885HSD17B10 1679/4885CYP1B1 1055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.