Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 4/20 | 0.47 |
| ▸ | PYGL | P06737 | 4/20 | 0.47 |
| ▸ | PYGM | P11217 | 4/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.47 |
| ▸ | KIT | P10721 | 2/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | AXL | P30530 | 1/20 | 0.47 |
| ▸ | MET | P08581 | 5/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 2/20 | 0.45 |
| ▸ | GPR6 | P46095 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780581 | 0.86 | RAB9A (0.47) | KDRPDGFRAKITFGFR2AXL | |
| SCHEMBL8780580 | 0.81 | CYP1A2 (0.50) | KDRPDGFRAKITFGFR2AXL | |
| SCHEMBL8780573 | 0.80 | P2RY1 (0.48) | METGPR6RAB9A | |
| SCHEMBL8780574 | 0.79 | NPC1 (0.49) | NPC1GAARAB9ASMN1; SMN2 | |
| SCHEMBL6452431 | 0.79 | KMT2A (0.61) | METGPR6FLT3 | |
| SCHEMBL8780572 | 0.77 | MET (0.47) | METGPR6NPC1GAARAB9A | |
| SCHEMBL8780568 | 0.77 | NPC1 (0.53) | NPC1GAARAB9ASMN1; SMN2 | |
| SCHEMBL7607256 | 0.75 | NPSR1 (0.69) | KDRPDGFRAKITAXLS1PR3 | |
| SCHEMBL19888870 | 0.72 | RAF1 (0.68) | KDRPDGFRAKITFGFR2AXL | |
| SCHEMBL19888733 | 0.71 | ABL1 (0.65) | KDRPDGFRAKITFGFR2AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0806414-A1 | Intermediates for herbicidal carboxamide derivatives | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1997-11-12 | — | — | EP | disclosed |