Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | ACHE | P22303 | 6/20 | 0.57 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 2/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 4/20 | 0.43 |
| ▸ | EP300 | Q09472 | 2/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL8373642 | 0.89 | ACHE (0.62) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| Diethylamine SCHEMBL8780599 | 0.87 | MEN1 (0.61) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| Diethylamine SCHEMBL8780596 | 0.86 | MAPT (0.88) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| SCHEMBL21232650 | 0.83 | MITF (0.65) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| Diethylamine SCHEMBL8377295 | 0.83 | MAPT (0.55) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| Diethylamine SCHEMBL8377307 | 0.82 | MAPT (0.55) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| Diethylamine SCHEMBL8780601 | 0.81 | ALDH1A1 (0.52) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| Dimethylamine SCHEMBL9633673 | 0.80 | ALDH1A1 (0.65) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| Diethylamine SCHEMBL5688882 | 0.79 | CYP1A2 (0.72) | ALDH1A1MAPTMAPK1KMT2AMEN1 | |
| Diethylamine SCHEMBL8780594 | 0.78 | ACHE (0.67) | ALDH1A1MAPTMAPK1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551697-B1 | Photoinitiator system and photopolymerizable composition using the same | HITACHI CHEMICAL CO LTD (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0551697-A1 | Photoinitiator system and photopolymerizable composition using the same | HITACHI CHEMICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| EP-0295044-B1 | PHOTOINITIATOR AND PHOTOPOLYMERIZABLE COMPOSITION USING THE SAME | Hitachi Chemical Co., Ltd. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-4987057-A | HIGH SENSITIVITY TO VISIBLE LIGHT RAYS | HITACHI CHEMICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |