Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.61 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.61 |
| ▸ | ACHE | P22303 | 6/20 | 0.54 |
| ▸ | MITF | O75030 | 1/20 | 0.54 |
| ▸ | F2 | P00734 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 2/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimethylamine SCHEMBL8373625 | 0.89 | ACHE (0.59) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL4471120 | 0.89 | ACHE (0.66) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL4471123 | 0.89 | ACHE (0.66) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| Diethylamine SCHEMBL8780592 | 0.87 | ALDH1A1 (0.64) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| Diethylamine SCHEMBL8780596 | 0.84 | MAPT (0.88) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL8780597 | 0.81 | ALDH1A1 (0.54) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL21232650 | 0.81 | MITF (0.65) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| Diethylamine SCHEMBL8377295 | 0.81 | MAPT (0.55) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| Diethylamine SCHEMBL8377307 | 0.80 | MAPT (0.55) | MEN1ALDH1A1MAPTMAPK1RAB9A | |
| SCHEMBL4468526 | 0.80 | ALDH1A1 (0.57) | MEN1ALDH1A1MAPTMAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551697-B1 | Photoinitiator system and photopolymerizable composition using the same | HITACHI CHEMICAL CO LTD (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0551697-A1 | Photoinitiator system and photopolymerizable composition using the same | HITACHI CHEMICAL CO., LTD. (JP) | 1993-07-21 | — | — | EP | disclosed |
| EP-0295044-B1 | PHOTOINITIATOR AND PHOTOPOLYMERIZABLE COMPOSITION USING THE SAME | Hitachi Chemical Co., Ltd. (JP) | 1992-04-22 | — | — | EP | disclosed |
| US-4987057-A | HIGH SENSITIVITY TO VISIBLE LIGHT RAYS | HITACHI CHEMICAL CO., LTD. (JP) | 1991-01-22 | — | — | US | disclosed |