Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.35 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780788 | 0.91 | GPR84 (0.39) | ALDH1A1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780948 | 0.82 | SLC22A2 (0.39) | ALDH1A1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780774 | 0.81 | KMT2A (0.46) | ALDH1A1RXFP1KMT2AMEN1GPR84 | |
| SCHEMBL8780873 | 0.81 | PLA2G7 (0.37) | ALDH1A1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780959 | 0.81 | SLC22A2 (0.40) | ALDH1A1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780809 | 0.78 | GPR84 (0.46) | ALDH1A1RXFP1KMT2AMEN1GPR84 | |
| SCHEMBL8780827 | 0.77 | SLC6A4 (0.44) | ALDH1A1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780897 | 0.76 | SLC22A2 (0.46) | ALDH1A1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780952 | 0.76 | SLC22A2 (0.37) | ALDH1A1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780867 | 0.74 | KCNH2 (0.43) | KCNH2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |