Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR5A | P47898 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | LSS | P48449 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780990 | 0.88 | KCNH2 (0.39) | LTA4HSMN1; SMN2KCNH2MCHR1 | |
| SCHEMBL8780868 | 0.88 | MAOB (0.41) | FDPSKDM4EALDH1A1HPGDKCNH2 | |
| SCHEMBL8781036 | 0.87 | KDM4E (0.44) | KDM4ESMN1; SMN2RXFP1LSSKMT2A | |
| SCHEMBL8780892 | 0.86 | RXFP1 (0.42) | RXFP1KMT2AKCNH2MCHR1 | |
| SCHEMBL8781032 | 0.86 | KDM4E (0.38) | LTA4HKDM4ESMN1; SMN2RXFP1KMT2A | |
| SCHEMBL8781045 | 0.85 | MAOB (0.49) | LTA4HKDM4EALDH1A1LSS | |
| SCHEMBL8780927 | 0.84 | KCNH2 (0.58) | SMN1; SMN2HPGDLSSKMT2AKCNH2 | |
| SCHEMBL8780850 | 0.83 | KCNH2 (0.59) | LTA4HSMN1; SMN2ALDH1A1HPGDKCNH2 | |
| SCHEMBL8780768 | 0.82 | ALDH1A1 (0.38) | LTA4HKDM4ESMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL8780867 | 0.81 | KCNH2 (0.43) | SMN1; SMN2KCNH2MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |