Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780841 | 0.89 | ALDH1A1 (0.43) | ALDH1A1HTTSMN1; SMN2BRPF1KMT2A | |
| SCHEMBL8780875 | 0.85 | ALDH1A1 (0.45) | ALDH1A1HTTSMN1; SMN2BRPF1KMT2A | |
| SCHEMBL8780781 | 0.82 | LTA4H (0.46) | ALDH1A1SMN1; SMN2KMT2ALTA4HKDM4E | |
| SCHEMBL8780868 | 0.80 | MAOB (0.41) | ALDH1A1KDM4ELMNA | |
| SCHEMBL8781045 | 0.80 | MAOB (0.49) | ALDH1A1LTA4HKDM4E | |
| SCHEMBL8780758 | 0.78 | LMNA (0.56) | ALDH1A1HTTSMN1; SMN2BRPF1KDM4E | |
| SCHEMBL8780796 | 0.77 | KDM4E (0.41) | ALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL8780811 | 0.76 | MAOB (0.41) | ALDH1A1SMN1; SMN2BRD4KDM4ELMNA | |
| SCHEMBL8780990 | 0.74 | KCNH2 (0.39) | SMN1; SMN2LTA4H | |
| SCHEMBL8780993 | 0.74 | THRA (0.40) | ALDH1A1KMT2AKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |