Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.36 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780781 | 0.88 | LTA4H (0.46) | KDM4EALDH1A1HPGDKCNH2MCHR1 | |
| SCHEMBL8780946 | 0.87 | ADORA2A (0.43) | MAOBMAOAADORA2AADORA1KDM4E | |
| SCHEMBL8780990 | 0.81 | KCNH2 (0.39) | ADORA2AADORA1KCNH2MCHR1 | |
| SCHEMBL8780768 | 0.80 | ALDH1A1 (0.38) | KDM4EALDH1A1LMNA | |
| SCHEMBL8781045 | 0.78 | MAOB (0.49) | MAOBKDM4EALDH1A1 | |
| SCHEMBL22831321 | 0.78 | CHRNB2 (0.51) | MAOBKDM4EALDH1A1LMNAKCNH2 | |
| SCHEMBL31623324 | 0.78 | CHRNB2 (0.51) | MAOBKDM4EALDH1A1LMNAKCNH2 | |
| SCHEMBL8780927 | 0.77 | KCNH2 (0.58) | LMNAHPGDKCNH2 | |
| SCHEMBL8780850 | 0.76 | KCNH2 (0.59) | ALDH1A1LMNAHPGDKCNH2 | |
| SCHEMBL8781036 | 0.75 | KDM4E (0.44) | ADORA2AADORA1KDM4EMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |