Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | ACHE | P22303 | 6/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.41 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780947 | 0.84 | HTR1A (0.39) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8781005 | 0.82 | KCNH2 (0.57) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780744 | 0.82 | SLC22A2 (0.48) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780861 | 0.81 | KCNH2 (0.61) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780915 | 0.78 | KCNH2 (0.57) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780890 | 0.78 | PKM (0.52) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780897 | 0.76 | SLC22A2 (0.46) | SLC22A2ADRB1SLC6A4KCNH2SLC47A2 | |
| SCHEMBL8780889 | 0.75 | SLC22A2 (0.40) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 | |
| SCHEMBL8780974 | 0.74 | DRD2 (0.42) | SIGMAR1 | |
| SCHEMBL8780923 | 0.74 | KCNH2 (0.56) | SIGMAR1SLC22A2ADRB1SLC6A4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |