Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.56 |
| ▸ | DRD4 | P21917 | 9/20 | 0.56 |
| ▸ | DRD3 | P35462 | 9/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | PLA2G7 | Q13093 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780898 | 0.88 | DRD4 (0.44) | DRD2DRD4DRD3 | |
| SCHEMBL8780960 | 0.84 | DRD2 (0.59) | DRD2DRD4DRD3KMT2ASLC6A4 | |
| SCHEMBL8780781 | 0.81 | LTA4H (0.46) | POLBKMT2ARXFP1PLA2G7 | |
| SCHEMBL8780892 | 0.79 | RXFP1 (0.42) | KMT2ARXFP1 | |
| SCHEMBL8781036 | 0.78 | KDM4E (0.44) | POLBKMT2ARXFP1SLC6A4PLA2G7 | |
| SCHEMBL8781032 | 0.77 | KDM4E (0.38) | POLBKMT2ARXFP1PLA2G7 | |
| SCHEMBL8780886 | 0.74 | CYP1A2 (0.47) | TSHRPOLBKMT2ARXFP1 | |
| SCHEMBL23067925 | 0.73 | DRD4 (0.76) | DRD2DRD4DRD3TSHRHTR1A | |
| SCHEMBL8780944 | 0.73 | TAAR1 (0.60) | TSHR | |
| Hydrochloric Acid SCHEMBL8042268 | 0.71 | DRD2 (0.97) | DRD2DRD4DRD3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |