Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 17/20 | 0.44 |
| ▸ | DRD2 | P14416 | 16/20 | 0.44 |
| ▸ | DRD3 | P35462 | 15/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | HEXA | P06865 | 1/20 | 0.38 |
| ▸ | HEXB | P07686 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8780906 | 0.88 | DRD2 (0.56) | DRD4DRD2DRD3 | |
| SCHEMBL8780960 | 0.84 | DRD2 (0.59) | DRD4DRD2DRD3PKM | |
| SCHEMBL8780808 | 0.84 | TAAR1 (0.45) | — | |
| SCHEMBL8780990 | 0.81 | KCNH2 (0.39) | DRD2DRD3PKM | |
| SCHEMBL8780919 | 0.80 | HRH3 (0.41) | PKM | |
| SCHEMBL8780789 | 0.79 | ADORA2A (0.41) | PKM | |
| SCHEMBL8780776 | 0.78 | MAOA (0.37) | DRD3PKM | |
| SCHEMBL8780750 | 0.78 | TDP1 (0.37) | PKM | |
| SCHEMBL8780867 | 0.78 | KCNH2 (0.43) | DRD2DRD3PKM | |
| SCHEMBL8780940 | 0.76 | ADORA2A (0.43) | PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0697407-B1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS (JP) | 1997-06-25 | — | — | EP | disclosed |
| EP-0697407-A1 | Pyrimidinedione derivatives and antiarrhythmic compositions containing same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-02-21 | — | — | EP | disclosed |