Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL442293 | 0.92 | MMP2 (0.44) | SMN1; SMN2ALDH1A1MMP2MMP9HSD17B10 | |
| SCHEMBL9322023 | 0.91 | HDAC1 (0.47) | SMN1; SMN2ALDH1A1HSD17B10TDP1TSHR | |
| SCHEMBL6291909 | 0.86 | PKM (0.47) | SMN1; SMN2ALDH1A1GAAPKMMMP2 | |
| SCHEMBL13384515 | 0.85 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1GAAPKMMMP2 | |
| SCHEMBL18451265 | 0.85 | GAA (0.48) | SMN1; SMN2ALDH1A1GAAPKMMMP2 | |
| SCHEMBL18918957 | 0.81 | MMP2 (0.46) | SMN1; SMN2PKMMMP2MMP9HSD17B10 | |
| SCHEMBL30852760 | 0.80 | ALDH1A1 (0.50) | ALDH1A1PKMMMP2MMP9 | |
| SCHEMBL1435917 | 0.80 | ALDH1A1 (0.50) | ALDH1A1PKMMMP2MMP9 | |
| SCHEMBL5544746 | 0.80 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1GAAPKMMMP2 | |
| SCHEMBL5031610 | 0.79 | MMP2 (0.44) | SMN1; SMN2MMP2MMP9HSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619179-A1 | MATRIX METALLOPROTEINASE INHIBITORS | Ranbaxy Laboratories Limited (IN) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038944-A1 | MATRIX METALLOPROTEINASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-03-29 | — | — | WO | disclosed |