Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9874246 | 0.71 | TAS1R3 (0.41) | MEN1KMT2AFLT1FLT4KDR | |
| SCHEMBL8984088 | 0.69 | MT-CO2 (0.45) | MEN1KMT2AFLT1FLT4KDR | |
| Hydrochloric Acid SCHEMBL9875354 | 0.68 | MT-CO2 (0.44) | MEN1KMT2AFLT1FLT4KDR | |
| Hydrochloric Acid SCHEMBL10351834 | 0.68 | ALDH1A1 (0.67) | HTTMEN1KMT2AALOX15SMN1; SMN2 | |
| SCHEMBL9013009 | 0.66 | POLB (0.37) | LMNAMEN1KMT2ANPSR1FLT1 | |
| SCHEMBL30804597 | 0.63 | KDM4E (0.55) | LMNAHTTMEN1KMT2AFLT1 | |
| SCHEMBL395135 | 0.63 | KDM4E (0.55) | LMNAHTTMEN1KMT2AFLT1 | |
| SCHEMBL30804592 | 0.63 | KDM4E (0.55) | LMNAHTTMEN1KMT2AFLT1 | |
| SCHEMBL8781634 | 0.63 | MAPT (0.47) | KMT2ANPSR1MAPK1HSD17B10RAB9A | |
| SCHEMBL8769018 | 0.62 | KDM4E (0.43) | LMNAMEN1KMT2AFLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499231-B1 | 9-Aminotetrahydroacridines and related compounds, a process for their preparation and their use as medicaments | HOECHST MARION ROUSSEL INC (US) | 1997-05-21 | — | — | EP | disclosed |
| US-5502203-A | FOR ACRIDINE COMPOUNDS USED IN TREATMENT OF ALZHEIMER*S DISEASE | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1996-03-26 | — | — | US | disclosed |
| US-5382594-A | Cognition activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1995-01-17 | — | — | US | disclosed |
| US-5210087-A | Cognition Activators | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1993-05-11 | — | — | US | disclosed |
| EP-0499231-A1 | 9-Aminotetrahydroacridines and related compounds, a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1992-08-19 | — | — | EP | disclosed |