Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.32 |
| ▸ | GAA | P10253 | 5/20 | 0.32 |
| ▸ | HPGD | P15428 | 5/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.30 |
| ▸ | CA12 | O43570 | 3/20 | 0.30 |
| ▸ | CA1 | P00915 | 3/20 | 0.30 |
| ▸ | CA2 | P00918 | 3/20 | 0.30 |
| ▸ | CA7 | P43166 | 3/20 | 0.30 |
| ▸ | CA9 | Q16790 | 3/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.30 |
| ▸ | MAPT | P10636 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8781822 | 0.76 | TSHR (0.34) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL16349333 | 0.70 | LMNA (0.42) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL12723239 | 0.67 | TSHR (0.39) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL817737 | 0.64 | ALDH1A1 (0.38) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL817874 | 0.62 | TSHR (0.37) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL11796042 | 0.60 | TSHR (0.45) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL12723240 | 0.60 | ADORA2B (0.37) | POLBKDM4ETDP1L3MBTL1TSHR | |
| SCHEMBL818261 | 0.60 | CYP1A2 (0.36) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL21776592 | 0.60 | LMNA (0.43) | ALDH1A1GAAHPGDHSD17B10POLB | |
| SCHEMBL15929799 | 0.60 | KDM4E (0.39) | ALDH1A1GAAHPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-B1 | New benzene derivatives having (NGF) production-promoting activity | SANKYO CO (JP) | 1997-01-22 | — | — | EP | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |