Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA7 | P43166 | 4/20 | 0.37 |
| ▸ | CA9 | Q16790 | 4/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16349333 | 0.79 | LMNA (0.42) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL1970857 | 0.71 | TSHR (0.35) | TSHRHSD17B10TDP1 | |
| SCHEMBL817874 | 0.70 | TSHR (0.37) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL817737 | 0.69 | ALDH1A1 (0.38) | TSHRLMNAKDM4EHPGDHTT | |
| SCHEMBL12723240 | 0.68 | ADORA2B (0.37) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL818261 | 0.68 | CYP1A2 (0.36) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL6633583 | 0.68 | TSHR (0.38) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL21776592 | 0.68 | LMNA (0.43) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL8782017 | 0.67 | ALDH1A1 (0.32) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL27314043 | 0.67 | GAA (0.42) | TSHRCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8716333-B2 | Process and compounds for the manufacture of oseltamivir and analogs thereof, and new antiviral agents | BROCK UNIVERSITY (CA) | 2014-05-06 | — | — | US | disclosed |
| US-8716333-B2 | Process and compounds for the manufacture of oseltamivir and analogs thereof, and new antiviral agents | BROCK UNIVERSITY (CA) | 2014-05-06 | — | — | US | disclosed |
| US-20120252890-A1 | PROCESS AND COMPOUNDS FOR THE MANUFACTURE OF OSELTAMIVIR AND ANALOGS THEREOF, AND NEW ANTIVIRAL AGENTS | BROCK UNIVERSITY (CA) | 2012-10-04 | — | — | US | disclosed |
| US-20120252890-A1 | PROCESS AND COMPOUNDS FOR THE MANUFACTURE OF OSELTAMIVIR AND ANALOGS THEREOF, AND NEW ANTIVIRAL AGENTS | BROCK UNIVERSITY (CA) | 2012-10-04 | — | — | US | disclosed |
| WO-2011047466-A1 | PROCESS AND COMPOUNDS FOR THE MANUFACTURE OF OSELTAMIVIR AND ANALOGS THEREOF, AND NEW ANTIVIRAL AGENTS | BROCK UNIVERSITY (CA) | 2011-04-28 | — | — | WO | disclosed |
| WO-2009137916-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF OSELTAMIVIR AND ANALOGS THEREOF | BROCK UNIVERSITY (CA) | 2009-11-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252890-A1 | PROCESS AND COMPOUNDS FOR THE MANUFACTURE OF OSELTAMIVIR AND ANALOGS THEREOF, AND NEW ANTIVIRAL AGENTS | NUDT1, ITPA, HAAO | TSHR 1549/4885CA12 2571/4885CA1 2733/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.