Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782909 | 0.92 | LMNA (0.40) | TP53KMT2AGPBAR1PDE4BPDE4A | |
| SCHEMBL8783851 | 0.88 | RORC (0.35) | TP53KMT2AMAPTPDE4BPDE4A | |
| SCHEMBL8782508 | 0.88 | KDM4E (0.37) | KMT2AGPBAR1PDE4BPDE4APDE4C | |
| SCHEMBL8783106 | 0.86 | GPBAR1 (0.39) | TP53KMT2AGPBAR1MAPTLMNA | |
| SCHEMBL8783507 | 0.83 | CNR1 (0.34) | KMT2AGPBAR1MAPTPDE4BPDE4A | |
| SCHEMBL8783286 | 0.82 | GPBAR1 (0.36) | GPBAR1MAPTPDE4BPDE4APDE4C | |
| SCHEMBL8782648 | 0.81 | HTR3E (0.39) | TP53HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL8782578 | 0.80 | PDE4A (0.36) | KMT2AGPBAR1PDE4BPDE4APDE4C | |
| SCHEMBL8782366 | 0.78 | HCRTR2 (0.43) | KMT2AMAPTLMNAMEN1HTR6 | |
| SCHEMBL8783310 | 0.77 | ALDH1A1 (0.33) | KMT2AMAPTPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493925-B1 | Pyrazole derivatives having herbicidal activity, their preparation and their use | SANKYO CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| EP-0493925-A1 | Pyrazole derivatives having herbicidal activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-07-08 | — | — | EP | disclosed |