Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 2/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | ACLY | P53396 | 2/20 | 0.34 |
| ▸ | STS | P08842 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783507 | 0.91 | CNR1 (0.34) | GPBAR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8782508 | 0.82 | KDM4E (0.37) | GPBAR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8782909 | 0.82 | LMNA (0.40) | GPBAR1HSD17B1HSD17B2PDE4APDE4B | |
| SCHEMBL8782864 | 0.82 | HSD17B1 (0.35) | GPBAR1HSD17B1HSD17B2ACLYSTS | |
| SCHEMBL8782289 | 0.82 | TP53 (0.39) | GPBAR1HSD17B1HSD17B2PDE4APDE4B | |
| SCHEMBL8782578 | 0.79 | PDE4A (0.36) | GPBAR1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8783310 | 0.76 | ALDH1A1 (0.33) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8783851 | 0.74 | RORC (0.35) | PDE4APDE4BPDE4CPDE4DCNR1 | |
| SCHEMBL8783890 | 0.74 | CNR1 (0.36) | GPBAR1ACLYCNR1HTR6MAPT | |
| SCHEMBL8783106 | 0.73 | GPBAR1 (0.39) | GPBAR1LMNAMAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0493925-B1 | Pyrazole derivatives having herbicidal activity, their preparation and their use | SANKYO CO (JP) | 1997-11-05 | — | — | EP | disclosed |
| US-5424279-A | Useful for rice crops | SANKYO COMPANY, LIMITED (JP) | 1995-06-13 | — | — | US | disclosed |
| EP-0493925-A1 | Pyrazole derivatives having herbicidal activity, their preparation and their use | Sankyo Company Limited (JP) | 1992-07-08 | — | — | EP | disclosed |