Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.34 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783166 | 0.90 | ABCG2 (0.39) | MEN1KMT2ATRPV1CNR1CNR2 | |
| SCHEMBL7772783 | 0.77 | FYN (0.43) | MEN1KMT2ATRPV1CNR1CNR2 | |
| SCHEMBL8783257 | 0.76 | TDP1 (0.36) | MEN1KMT2AABCG2RAB9AL3MBTL1 | |
| SCHEMBL7774902 | 0.74 | RAB9A (0.50) | MEN1KMT2APKMHTTRAB9A | |
| SCHEMBL8783252 | 0.73 | ABCG2 (0.34) | MEN1KMT2AABCG2RAB9AKCNJ6 | |
| SCHEMBL7348668 | 0.72 | POLB (0.40) | MEN1KMT2AABCG2NPC1SMN1; SMN2 | |
| SCHEMBL8784604 | 0.71 | ABCG2 (0.39) | MEN1KMT2AABCG2HPGDNPC1 | |
| SCHEMBL30866160 | 0.70 | ALDH1A1 (0.44) | MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL35967 | 0.69 | ALDH1A1 (0.48) | MEN1KMT2ARAB9ANPC1 | |
| SCHEMBL5490742 | 0.66 | ALDH1A1 (0.50) | MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760814-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1997-03-12 | — | — | EP | claimed |
| WO-1995032961-A1 | A PROCESS FOR PREPARING 1-BUTYL-2-[2'-(2H-TETRAZOL-5-YL)-BIPHENYL-4-YLMETHYL]-1H-INDOLE-3-CARBOXYLIC ACID | SYNTEX (U.S.A.) INC. (US) | 1995-12-07 | — | — | WO | claimed |