Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8783932 | 0.79 | HSD11B1 (0.48) | RAB9AALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL8784702 | 0.74 | KCNH2 (0.54) | POLBCYP2D6CYP2C19CA1CA2 | |
| SCHEMBL6566282 | 0.72 | ALDH1A1 (0.56) | ALDH1A1NPSR1POLBLMNACYP1A2 | |
| SCHEMBL8783649 | 0.71 | HRH3 (0.53) | ALDH1A1MEN1KMT2ALMNATDP1 | |
| SCHEMBL27718210 | 0.70 | ALDH1A1 (0.60) | RAB9AALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL4618441 | 0.70 | SFRP1 (0.59) | RAB9AMEN1KMT2AMAPTLMNA | |
| SCHEMBL13297964 | 0.69 | RAB9A (0.69) | RAB9AALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL29115758 | 0.68 | CYP2C9 (0.68) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL19454509 | 0.68 | ALDH1A1 (0.73) | RAB9AALDH1A1MEN1KMT2APOLB | |
| SCHEMBL13983251 | 0.68 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2ANPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663414-A | INHIBITS PHOSPHOLIPASE ACTIVITY; ANTIISCHEMIC AGENTS; TREATMENT OF CARDIAC INFRACTION | EISAI CO., LTD. (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0468054-B1 | BENZENESULFONAMIDE DERIVATIVE | EISAI CO LTD (JP) | 1997-05-28 | — | — | EP | disclosed |
| US-5530118-A | PHOSPHOLIPASE INHIBITOR | EISAI CO., LTD. (JP) | 1996-06-25 | — | — | US | disclosed |
| EP-0468054-A1 | BENZENESULFONAMIDE DERIVATIVE | Eisai Co., Ltd. (JP) | 1992-01-29 | — | — | EP | disclosed |