Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | STAT3 | P40763 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6566997 | 0.76 | KMT2A (0.79) | ALDH1A1KDM4ESMN1; SMN2LMNATSHR | |
| SCHEMBL1873887 | 0.76 | PRMT1 (0.77) | ALDH1A1POLBSMN1; SMN2LMNATSHR | |
| SCHEMBL1881276 | 0.75 | KEAP1 (0.53) | ALDH1A1KDM4EHSD17B10KEAP1POLB | |
| SCHEMBL17472731 | 0.75 | PTGER2 (0.53) | — | |
| SCHEMBL6568083 | 0.73 | ALDH1A1 (0.54) | ALDH1A1KDM4EKEAP1POLBSMN1; SMN2 | |
| SCHEMBL6026817 | 0.72 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL29967633 | 0.72 | KDM4E (1.00) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL8784391 | 0.72 | RAB9A (0.52) | ALDH1A1POLBLMNANPSR1CYP1A2 | |
| SCHEMBL943003 | 0.72 | SMN1; SMN2 (0.64) | HSD17B10SMN1; SMN2NPSR1CYP3A4L3MBTL1 | |
| SCHEMBL13090623 | 0.71 | SMN1; SMN2 (0.55) | SMN1; SMN2CYP1A2CYP3A4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1443041-A1 | 5-AMIDINO-2-HYDROXYBENZENESULFONAMIDE DERIVATIVES, MEDICINAL COMPOSITIONS CONTAINING THE SAME, MEDICINAL USE THEREOF AND INTERMEDIATES IN THE PRODUCTION THEREOF | Kissei Pharmaceutical Co., Ltd. (JP) | 2004-08-04 | — | — | EP | disclosed |