Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.42 |
| ▸ | NPC1 | O15118 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787834 | 0.89 | TNKS (0.46) | MAOBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8787875 | 0.88 | MAOB (0.55) | MAOBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8788322 | 0.80 | NPC1 (0.40) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8787416 | 0.79 | ALDH1A1 (0.49) | MAOBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8787318 | 0.76 | TNKS (0.60) | MAOBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8787178 | 0.76 | SMN1; SMN2 (0.49) | MAOBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8787165 | 0.75 | RAB9A (0.63) | MAOBSMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL8787867 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL8787268 | 0.73 | MAOB (0.47) | MAOBGRM4 | |
| SCHEMBL8788339 | 0.72 | NPC1 (0.44) | SMN1; SMN2NPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |