Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 10/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.40 |
| ▸ | RAB9A | P51151 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | STAT6 | P42226 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.39 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8787965 | 0.89 | SMN1; SMN2 (0.50) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8787178 | 0.88 | SMN1; SMN2 (0.49) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8788347 | 0.80 | MAOB (0.42) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8788422 | 0.78 | NPC1 (0.51) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8787165 | 0.78 | RAB9A (0.63) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8788270 | 0.76 | SMN1; SMN2 (0.60) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8787834 | 0.75 | TNKS (0.46) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8788300 | 0.75 | MAPT (0.38) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8787924 | 0.74 | AMY1A (0.49) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 | |
| SCHEMBL8787512 | 0.72 | ALDH1A1 (0.47) | NPC1SMN1; SMN2RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758649-A1 | Chromone derivative, process for preparing same and pharmaceutical composition | Kureha Chemical Industry Co., Ltd. (JP) | 1997-02-19 | — | — | EP | disclosed |