Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788103 | 0.78 | ADRB1 (0.47) | MAPTKDM4EALDH1A1 | |
| SCHEMBL8098928 | 0.76 | MAPT (0.44) | MAPTOPRM1OPRL1DPP4MEN1 | |
| SCHEMBL8787513 | 0.73 | KDM4E (0.45) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL15993850 | 0.73 | KDM4E (0.56) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8787935 | 0.72 | ALDH1A1 (0.39) | MAPTALDH1A1GAA | |
| SCHEMBL31074188 | 0.72 | TDO2 (0.48) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL18979270 | 0.72 | MAPT (0.48) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL1578382 | 0.71 | MAPT (0.48) | MAPTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8788804 | 0.71 | CA2 (0.41) | MAPTALDH1A1DPP4 | |
| SCHEMBL8103368 | 0.71 | MAPT (0.49) | MAPTKDM4ESMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |