Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LCAT | P04180 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8788310 | 0.75 | AR (0.46) | MAPTPARP1ACACBAR | |
| SCHEMBL8788103 | 0.75 | ADRB1 (0.47) | MAPTALDH1A1LCATEGLN2 | |
| SCHEMBL8787612 | 0.73 | P2RX7 (0.38) | CA2CHKAP2RX7LCATPARP1 | |
| SCHEMBL8788652 | 0.71 | MAPT (0.50) | MAPTALDH1A1DPP4 | |
| SCHEMBL8788549 | 0.69 | LCAT (0.42) | CA2CHKAP2RX7ALDH1A1LCAT | |
| SCHEMBL8090313 | 0.67 | MAPT (0.44) | MAPTALDH1A1 | |
| Formic Acid SCHEMBL27795592 | 0.66 | P2RX7 (0.41) | CA2CHKAP2RX7ALDH1A1LCAT | |
| SCHEMBL17723675 | 0.65 | PIM1 (0.37) | CA2CHKAP2RX7LCATPARP1 | |
| SCHEMBL8787841 | 0.65 | CYP11B2 (0.40) | MAPTLCATACACB | |
| SCHEMBL27264896 | 0.64 | CA2 (0.68) | CA2CHKAALDH1A1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |