Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 3/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789455 | 0.87 | ALDH1A1 (0.58) | ALDH1A1TSHRHTTMAPK1MAPT | |
| SCHEMBL8789825 | 0.70 | PKM (0.56) | ALDH1A1TSHRHTTMAPTGAA | |
| SCHEMBL8788933 | 0.70 | ALDH1A1 (0.46) | ALDH1A1TSHRHTTMAPK1MAPT | |
| SCHEMBL5954446 | 0.68 | ALDH1A1 (0.63) | ALDH1A1MAPTGAAHSD17B10MEN1 | |
| SCHEMBL8799012 | 0.68 | CA2 (0.46) | ALDH1A1MAPK1MAPTHSD17B10MEN1 | |
| SCHEMBL10676845 | 0.68 | MEN1 (0.51) | ALDH1A1TSHRHTTMAPTHSD17B10 | |
| SCHEMBL8973617 | 0.66 | PKM (0.41) | ALDH1A1TSHRHTTGAALMNA | |
| SCHEMBL10680922 | 0.66 | KMT2A (0.57) | HTTKMT2ACYP2C19 | |
| SCHEMBL10672409 | 0.66 | KMT2A (0.51) | ALDH1A1TSHRMAPK1MAPTLMNA | |
| SCHEMBL10681934 | 0.66 | RXFP1 (0.48) | ALDH1A1TSHRMAPK1MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788796-A1 | URICOSURIC AGENT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |