Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LCAT | P04180 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8789208 | 0.82 | OPRM1 (0.36) | ATMOPRM1OPRL1ALDH1A1HTT | |
| SCHEMBL8787492 | 0.74 | ALDH1A1 (0.39) | ATMOPRM1OPRL1ALDH1A1HTT | |
| SCHEMBL8788467 | 0.71 | LMNA (0.34) | OPRM1OPRL1ALDH1A1HTTMEN1 | |
| SCHEMBL8788663 | 0.71 | LCAT (0.40) | ATMOPRM1OPRL1ALDH1A1HTT | |
| SCHEMBL7622250 | 0.71 | ATM (0.39) | ATMOPRM1OPRL1ALDH1A1HTT | |
| SCHEMBL7622254 | 0.71 | ATM (0.39) | ATMOPRM1OPRL1ALDH1A1HTT | |
| SCHEMBL11819034 | 0.67 | HTT (0.42) | ATMOPRM1OPRL1ALDH1A1HTT | |
| SCHEMBL12507023 | 0.65 | OPRM1 (0.36) | ATMOPRM1OPRL1ALDH1A1HTT | |
| SCHEMBL8787883 | 0.65 | OPRM1 (0.39) | OPRM1LCAT | |
| SCHEMBL10732284 | 0.65 | L3MBTL1 (0.39) | ALDH1A1HTTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1341594-A | Substituted pyrrolidone, thiazolidone or oxazolidone as herbicide | ZENECA LTD (GB) | 2002-03-27 | — | — | CN | disclosed |
| CN-1153512-A | Substituted pyrrolidones, thiazolidinones or oxazolidinones as herbicides | ZENECA LTD (GB) | 1997-07-02 | — | — | CN | disclosed |
| EP-0763020-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1997-03-19 | — | — | EP | disclosed |
| WO-1995033719-A1 | SUBSTITUTED PYRROLIDONE, THIAZOLIDONES OR OXAZOLIDONES AS HERBICIDES | ZENECA LIMITED (GB) | 1995-12-14 | — | — | WO | disclosed |