SCHEMBL879088

SCHEMBL879088

CC(C)(N)CCOC(C)(C)C

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 1/20 0.33
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26712026 0.86
SCHEMBL24044983 0.85
SCHEMBL25897933 0.84 MAPK1 (0.32) MAPK1
SCHEMBL18583240 0.82 GRM4 (0.33) GRM4
SCHEMBL24571110 0.79 SMPD1 (0.31)
SCHEMBL24906756 0.78 GRM4 (0.31) GRM4
SCHEMBL21917242 0.78 GRM4 (0.31) GRM4
SCHEMBL19772674 0.78 GRM4 (0.31) GRM4
SCHEMBL805401 0.76 ALDH1A1 (0.38) GRM4
SCHEMBL18714174 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11692079-B2 2-dimensional MXene particle surface-modified with functional group containing saturated or unsaturated hydrocarbon, preparation method thereof and use thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2023-07-04 US disclosed
US-20230129118-A1 PHYTOSPHINGOSINE DERIVATIVES AS ADJUVANTS IN IMMUNE STIMULATION Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2023-04-27 US disclosed
EP-3175033-B1 COMPOSITIONS FOR TREATMENT OF FIBER MATERIALS HUNTSMAN TEXTILE EFFECTS GERMANY GMBH (DE) 2023-04-26 EP disclosed
US-20230115871-A1 A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS HANGZHOU DAC BIOTECH CO., LTD (CN) 2023-04-13 US disclosed
US-20230025327-A1 CONJUGATES OF TUBULYSIN DERIVATIVES AND CELL BINDING MOLECULES AND METHODS OF MAKING HANGZHOU DAC BIOTECH CO., LTD. (CN) 2023-01-26 US disclosed
US-20230000994-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES YALE UNIVERSITY 2023-01-05 US disclosed
US-20220409612-A1 TREATMENT OF CANCER ELLIPSES PHARMA LTD (GB) 2022-12-29 US disclosed
WO-2021255287-A1 PHYTOSPHINGOSINE DERIVATIVES AS ADJUVANTS IN IMMUNE STIMULATION Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2021-12-23 WO disclosed
US-11173211-B2 Compounds and methods for the targeted degradation of rapidly accelerated Fibrosarcoma polypeptides ARVINAS OPERATIONS, INC. (US) 2021-11-16 US disclosed
WO-2021212638-A1 CONJUGATES OF A CELL-BINDING MOLECULE WITH CAMPTOTHECIN ANALOGS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2021-10-28 WO disclosed
WO-2012082995-A1 OLIGOMER-CONTAINING HYDANTOIN COMPOUNDS NEKTAR THERAPEUTICS (US) 2012-06-21 WO disclosed
US-8143366-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2012-03-27 US disclosed
US-8063015-B2 Glycopegylation methods and proteins/peptides produced by the methods NOVO NORDISK A/S (DK) 2011-11-22 US disclosed
US-20110227002-A1 AROMATIC IMIDE-BASED DISPERSANT FOR CARBON NANOTUBES AND CARBON NANOTUBE COMPOSITION COMPRISING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2011-09-22 US disclosed
US-20100081782-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME EKWURIBE NNOCHIRI N 2010-04-01 US disclosed
US-20100048456-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS NOVO NORDISK A/S (DK) 2010-02-25 US disclosed
US-7625995-B2 Aryl carbamate oligomers for hydrolyzable prodrugs and prodrugs comprising same BIOCON LIMITED (IN) 2009-12-01 US disclosed
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME BIOCON LIMITED (IN) 2008-06-19 US disclosed
WO-2007137260-A2 PREPARATION OF POLYMER CONJUGATES OF VLA-4 ANTAGONISTS VIA A MITSUNOBU' S REACTION ELAN PHARMACEUTICALS, INC. (US) 2007-11-29 WO disclosed
WO-2007102705-A1 ANION RECEPTOR AND ELECTROLYTE USING THE SAME KIM HEE JUNG (KR) 2007-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11173211-B2 Compounds and methods for the targeted degradation of rapidly accelerated Fibrosarcoma polypeptides CRBN, ARAF, VHL GRM4 4728/4885MAPK1 2843/4885
US-20080146778-A1 ARYL CARBAMATE OLIGOMERS FOR HYDROLYZABLE PRODRUGS AND PRODRUGS COMPRISING SAME ALK, AOX1, OGFR GRM4 1323/4885MAPK1 3153/4885
US-20230000994-A1 COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF RAPIDLY ACCELERATED FIBROSARCOMA POLYPEPTIDES CRBN, ARAF, VHL GRM4 4728/4885MAPK1 2843/4885
US-20230115871-A1 A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS CD2BP2, EPCAM, CD74 GRM4 3278/4885MAPK1 3202/4885
US-20110227002-A1 AROMATIC IMIDE-BASED DISPERSANT FOR CARBON NANOTUBES AND CARBON NANOTUBE COMPOSITION COMPRISING THE SAME EWSR1, NES, CENPE GRM4 4542/4885MAPK1 2879/4885
US-20230025327-A1 CONJUGATES OF TUBULYSIN DERIVATIVES AND CELL BINDING MOLECULES AND METHODS OF MAKING TEK, TEKT1, EPCAM GRM4 2716/4885MAPK1 3404/4885
US-20230129118-A1 PHYTOSPHINGOSINE DERIVATIVES AS ADJUVANTS IN IMMUNE STIMULATION UGCG, PA2G4, IL4 GRM4 260/4885MAPK1 2021/4885
US-20220409612-A1 TREATMENT OF CANCER DDX1, CDC73, CBX2 GRM4 4052/4885MAPK1 4449/4885
US-20100048456-A1 GLYCOPEGYLATION METHODS AND PROTEINS/PEPTIDES PRODUCED BY THE METHODS PTMS, ANPEP, NGLY1 GRM4 2865/4885MAPK1 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.