Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | CACNA1G | O43497 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL204285 | 0.78 | NPC1 (0.46) | HTR2CHTR2B | |
| SCHEMBL9709040 | 0.77 | RAB9A (0.52) | MC4RHPGDUSP2ALDH1A1HTT | |
| SCHEMBL23885597 | 0.74 | P2RX7 (0.51) | — | |
| SCHEMBL7874030 | 0.72 | HTR2C (0.77) | MC4RHPGDUSP2ALDH1A1HTR2C | |
| SCHEMBL1789145 | 0.72 | HTR2C (0.77) | MC4RHPGDUSP2ALDH1A1HTR2C | |
| SCHEMBL5154669 | 0.72 | HTR2C (0.77) | MC4RHPGDUSP2ALDH1A1HTR2C | |
| SCHEMBL10411479 | 0.71 | ALPI (0.49) | DPP4 | |
| SCHEMBL10411481 | 0.71 | ALPI (0.49) | DPP4 | |
| SCHEMBL1792830 | 0.71 | MC4R (0.75) | MC4RHPGDUSP2ALDH1A1TSHR | |
| SCHEMBL526330 | 0.71 | ALDH1A1 (0.73) | MC4RHPGDUSP2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1997-11-12 | — | — | EP | disclosed |
| WO-1996022966-A1 | CELL ADHESION INHIBITORS | BIOGEN, INC. (US) | 1996-08-01 | — | — | WO | disclosed |