Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8790882 | 0.77 | MC4R (0.55) | MC4RALDH1A1HPGDUSP2HTT | |
| SCHEMBL7779326 | 0.75 | MEN1 (0.42) | MEN1KMT2AALDH1A1 | |
| SCHEMBL9709150 | 0.73 | FAAH (0.39) | MEN1KMT2AMAPT | |
| SCHEMBL5265103 | 0.72 | RAB9A (0.73) | RAB9ANPC1GAAFUCA1POLB | |
| SCHEMBL21162505 | 0.72 | MC4R (0.52) | RAB9ANPC1GAAFUCA1POLB | |
| SCHEMBL7942663 | 0.72 | MC4R (0.36) | MC4RMEN1KMT2AHPGD | |
| SCHEMBL228875 | 0.72 | POLB (0.44) | POLB | |
| Hydrochloric Acid SCHEMBL1532746 | 0.71 | RAB9A (0.71) | RAB9ANPC1GAAFUCA1POLB | |
| SCHEMBL13381633 | 0.71 | GLA (0.61) | RAB9ANPC1GAAPOLBMEN1 | |
| SCHEMBL9604373 | 0.70 | NPY1R (0.42) | RAB9ANPC1GAAPOLBMC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020665-A1 | THIAZOLIDINE DERIVATIVES AND THEIR USE IN THERAPY | GLAXO GROUP LIMITED (GB) | 1992-11-26 | — | — | WO | disclosed |