Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.57 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.57 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8916330 | 0.91 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL8913829 | 0.90 | AGTR1 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8326292 | 0.90 | AGTR1 (0.59) | AGTR1AGTR2GP6 | |
| SCHEMBL8913822 | 0.89 | AGTR1 (0.58) | AGTR1AGTR2GP6 | |
| SCHEMBL359 | 0.88 | GP6 (0.63) | AGTR1AGTR2GP6 | |
| SCHEMBL8914300 | 0.88 | AGTR2 (0.64) | AGTR1AGTR2 | |
| SCHEMBL8792485 | 0.86 | AGTR1 (0.64) | AGTR1AGTR2GP6 | |
| SCHEMBL8913133 | 0.82 | ALDH1A1 (0.50) | AGTR1AGTR2 | |
| SCHEMBL9694822 | 0.80 | AGTR1 (0.57) | AGTR1AGTR2GP6 | |
| SCHEMBL8912755 | 0.80 | GP6 (0.55) | AGTR1AGTR2GP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6016659-A | — | — | None | — | — | JP | disclosed |
| EP-0693478-B1 | Quinoline compounds | GREEN CROSS CORP (JP) | 1998-08-12 | — | — | EP | disclosed |
| US-5665881-A | CARDIOVASCULAR DISORDERS, HYPOTENSIVE, ANGIOTENSIN II ANTAGONIST | THE GREEN CROSS CORPORATION (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0693478-A1 | Quinoline compounds | THE GREEN CROSS CORPORATION (JP) | 1996-01-24 | — | — | EP | disclosed |
| US-5478832-A | Angiotensin II antagonists; cardiovascular disorders | THE GREEN CROSS CORPORATION (JP) | 1995-12-26 | — | — | US | disclosed |
| JP-H0616659-A | QUINOLINE DERIVATIVE | ASAHI GLASS CO LTD | 1994-01-25 | — | — | JP | disclosed |
| EP-0569013-A1 | Quinoline compounds as angiotensin II antagonists | THE GREEN CROSS CORPORATION (JP) | 1993-11-10 | — | — | EP | disclosed |
| JP-H00616659-A | — | — | 0001-01-01 | — | — | JP | disclosed |