Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 3/20 | 0.48 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.41 |
| ▸ | QDPR | P09417 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28347412 | 0.80 | ALDH1A1 (0.47) | ALOX15CYP3A4ALOX5ALDH1A1CA1 | |
| SCHEMBL9505716 | 0.78 | MAPT (0.38) | MAPTNPC1POLBRAB9ACYP3A4 | |
| SCHEMBL29291587 | 0.76 | CA9 (0.50) | MAPTNPC1POLBKDM4EMEN1 | |
| SCHEMBL16761044 | 0.76 | ALOX15 (0.44) | ALOX15KDM4EALDH1A1GAAHPGD | |
| SCHEMBL29291586 | 0.76 | TRPA1 (0.52) | MAPTNPC1RAB9AALOX15HSD17B10 | |
| SCHEMBL29291588 | 0.76 | ALDH1A1 (0.50) | MAPTPOLBALOX15HSD17B10CYP3A4 | |
| SCHEMBL19491999 | 0.75 | NPC1 (0.57) | MAPTNPC1POLBRAB9AALOX15 | |
| SCHEMBL20227392 | 0.73 | NPC1 (0.66) | MAPTNPC1POLBRAB9AALOX15 | |
| SCHEMBL7928315 | 0.73 | TTR (0.42) | MAPTPOLBRAB9AALOX15HSD17B10 | |
| SCHEMBL21589350 | 0.72 | ALDH1A1 (0.55) | HSD17B10KDM4EALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591250-A | POLYIMIDE MEMBRANE | GAS RESEARCH INSTITUTE (US) | 1997-01-07 | — | — | US | disclosed |