Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 8/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30863330 | 0.87 | RAF1 (0.51) | RAF1MAPK14KDM4EHPGDPOLB | |
| SCHEMBL31686438 | 0.87 | RAF1 (0.51) | RAF1MAPK14KDM4EHPGDPOLB | |
| SCHEMBL379112 | 0.87 | RAF1 (0.51) | RAF1MAPK14KDM4EHPGDPOLB | |
| SCHEMBL30863324 | 0.87 | RAF1 (0.51) | RAF1MAPK14KDM4EHPGDPOLB | |
| SCHEMBL30667490 | 0.83 | RAB9A (0.59) | RAF1MAPK14KDM4EHPGDBRAF | |
| SCHEMBL379862 | 0.83 | RAB9A (0.59) | RAF1MAPK14KDM4EHPGDBRAF | |
| SCHEMBL31440788 | 0.83 | KMT2A (0.61) | RAF1MAPK14KDM4EHPGDPOLB | |
| SCHEMBL379165 | 0.81 | RAF1 (0.47) | RAF1MAPK14KDM4EHPGDPOLB | |
| SCHEMBL4534203 | 0.81 | RAF1 (0.47) | RAF1MAPK14KDM4EHPGDPOLB | |
| SCHEMBL15229756 | 0.81 | RAF1 (0.47) | RAF1MAPK14KDM4EHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120130072-A1 | PROCESS FOR THE PREPARATION OF DIHYDROQUINAZOLINES | AICURIS GMBH & CO. KG (DE) | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120130072-A1 | PROCESS FOR THE PREPARATION OF DIHYDROQUINAZOLINES | QDPR, DHPS, DHX15 | RAF1 2551/4885MAPK14 1667/4885KDM4E 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.