Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568850 | 0.80 | TDP1 (0.68) | LMNAALDH1A1TDP1NPSR1POLB | |
| SCHEMBL8795091 | 0.78 | ALDH1A1 (0.44) | LMNAALDH1A1TDP1NPSR1KMT2A | |
| SCHEMBL8795729 | 0.76 | ALDH1A1 (0.38) | ALDH1A1NPSR1POLBKMT2AMAPT | |
| SCHEMBL9004420 | 0.75 | MAPT (0.49) | LMNAALDH1A1TDP1NPSR1KMT2A | |
| SCHEMBL8795437 | 0.74 | ALDH1A1 (0.40) | LMNAALDH1A1TDP1NPSR1POLB | |
| SCHEMBL11879865 | 0.72 | ALDH1A1 (0.55) | LMNAALDH1A1TDP1NPSR1POLB | |
| SCHEMBL8794905 | 0.72 | TSHR (0.49) | ALDH1A1TDP1NPSR1POLBKMT2A | |
| SCHEMBL8795503 | 0.71 | LMNA (0.45) | LMNAALDH1A1NPSR1POLBKMT2A | |
| SCHEMBL1111522 | 0.70 | POLB (0.47) | ALDH1A1NPSR1POLBKMT2AMAPT | |
| Dimethylamine SCHEMBL10653757 | 0.70 | NPSR1 (0.58) | LMNAALDH1A1TDP1NPSR1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0586405-B1 | NOVEL 2H-BENZO[b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS | BEIERSDORF LILLY GMBH (DE) | 1997-09-10 | — | — | EP | disclosed |
| EP-0586405-A1 | NOVEL 2H-BENZO b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS. | BEIERSDORF LILLY GMBH (DE) | 1994-03-16 | — | — | EP | disclosed |
| WO-1992020671-A1 | NOVEL 2H-BENZO[b]PYRANE DERIVATIVES SUBSTITUTED IN THE 4 POSITION BY ARYL OR N-HETEROARYL, PROCESS FOR PRODUCING THEM AND PREPARATIONS CONTAINING THE COMPOUNDS | BEIERSDORF-LILLY GMBH (DE) | 1992-11-26 | — | — | WO | disclosed |