Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31398577 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TDP1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8795405 | 0.75 | MAPT (0.51) | ALDH1A1NPSR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL8795096 | 0.74 | NPSR1 (0.47) | ALDH1A1TDP1NPSR1KMT2AMEN1 | |
| SCHEMBL8795019 | 0.74 | LMNA (0.48) | ALDH1A1TDP1NPSR1KMT2AMEN1 | |
| SCHEMBL8628902 | 0.71 | MAPT (0.38) | ALDH1A1TDP1NPSR1KMT2ASMN1; SMN2 | |
| SCHEMBL8795346 | 0.71 | HIF1A (0.45) | ALDH1A1TDP1NPSR1KMT2ASMN1; SMN2 | |
| SCHEMBL8795165 | 0.70 | NPSR1 (0.42) | ALDH1A1TDP1NPSR1KMT2AMEN1 | |
| SCHEMBL8794504 | 0.70 | ATM (0.50) | ALDH1A1NPSR1KMT2ASMN1; SMN2MEN1 | |
| SCHEMBL11879865 | 0.69 | ALDH1A1 (0.55) | ALDH1A1TDP1NPSR1KMT2ASMN1; SMN2 | |
| SCHEMBL708655 | 0.69 | KMT2A (0.53) | ALDH1A1TDP1NPSR1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0645386-B1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1997-12-29 | — | — | EP | disclosed |
| EP-0645386-A1 | N-Azinyl-N'-(het)arylsulfonylureas as herbicides | BAYER AG (DE) | 1995-03-29 | — | — | EP | disclosed |