Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782071 | 0.91 | ALDH1A1 (0.45) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL10496017 | 0.84 | MEN1 (0.43) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL6073675 | 0.77 | ALDH1A1 (0.52) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL9680510 | 0.76 | ALDH1A1 (0.52) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL19283724 | 0.76 | LMNA (0.54) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL6074622 | 0.76 | ALDH1A1 (0.56) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL10777713 | 0.74 | FAAH (0.54) | MEN1LMNAKMT2AALDH1A1TDP1 | |
| SCHEMBL11286980 | 0.74 | FAAH (0.48) | MEN1LMNAKMT2AALDH1A1TDP1 | |
| SCHEMBL10343485 | 0.74 | LMNA (0.58) | MEN1LMNABLMHBBKMT2A | |
| SCHEMBL1679439 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0657456-B1 | Process for preparing epibatidine | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1997-06-04 | — | — | EP | disclosed |
| EP-0736534-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-10-09 | — | — | EP | disclosed |
| US-5545741-A | Process for the preparation of epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1996-08-13 | — | — | US | disclosed |
| EP-0657456-A1 | Process for preparing epibatidine | EGIS GYOGYSZERGYAR RT. (HU) | 1995-06-14 | — | — | EP | disclosed |
| EP-0657455-A1 | Epi-epibatidine derivatives, a process and intermediates for preparing them and epi-epibatidine and medicaments containing the epi-epibatidine derivatives and/or epi-epibatidine and the use of them | EGIS GYOGYSZERGYAR (HU) | 1995-06-14 | — | — | EP | disclosed |